Gargiulo suffered a season-ending ACL in the preseason, eliminating a swing-guard/center candidate who had been competing for depth on Denver's interior line. His absence raises roster and depth concerns, with the Broncos likely needing a short-term plan at guard/center ahead of cuts and Week 1 preparations.

Gargiulo, a seventh-round pick from South Carolina, suffered a leg injury in preseason and will be placed on injured reserve, ending his season. His absence leaves the Broncos thinner at guard, elevating Throckmorton and Sherman into larger roles. Gargiulo had been pushing for a roster spot after a strong camp, and his loss removes a young interior option from the team’s depth chart.

Gargiulo, a 6-5, 310-pound tackle/guard from South Carolina, was a seventh-round pick vying for a swing-guard/center role. Knee injury in preseason against Arizona ends 2025 season; IR seals inability to return this year; Broncos move to fill his spot with Prentice as interior depth adds a blocking option.

Gargiulo left the game with a knee issue after a third-quarter cart, signaling concern around Denver’s backup swing guard/center competition. His injury could open more chances for teammates in the reserve line, shaping the Broncos’ depth chart as they head toward the Saints game.

Gargiulo suffered a knee injury in the third quarter of the Broncos' preseason win over the Cardinals, leaving Denver with interior-line depth concerns as he heads toward an injury timeline. The seventh-round pick from South Carolina/Yale had been vying for a swing guard/center role after spending his rookie season on Denver's practice squad.